Tuesday, 16 January, 2018

Ibuprofen Use Linked to Compensated Hypogonadism in Males

Popping ibuprofen could make your balls shrivel Ibuprofen Use Linked to Compensated Hypogonadism in Males
Carol Daniels | 10 January, 2018, 01:23

Epidemiological studies have shown that NSAID exposure was associated with reduced testosterone and congenital malformations; another study showed a drop in a testosterone metabolite among men who were taking ibuprofen regularly. The scientist tested aspirin, Tylenol and ibuprofen.

However, despite the change in LH levels, the men's testosterone levels didn't change.

After six weeks, the men who took ibuprofen had disrupted production of their male sex hormones, which led to a condition called "compensated hypogonadism". The condition arises when the body has to boost levels of testosterone because normal production in the testes has fallen.

The researchers found that prolonged ibuprofen use suppressed "important aspects of testicular function, including testosterone production".

Researchers conducted a relatively small study that included men aged 18 to 35 and found that those who used the common over-the-counter drug developed hormonal imbalances that can cause a reduction in fertility, CBS news reported.

To avoid these side-effects, doctors caution against taking Ibuprofen for more longer than ten days in a row, per the FDA's warning. The men were then divided into two groups, 14 in an ibuprofen group and 17 in a placebo group.

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However, in recent years, ibuprofen in particular has been linked to an increased risk of heart attacks and strokes, meaning we should be more cautious when taking anti-inflammatory drugs.

The study comes as several studies show that infertility rates are on the rise in several areas of the world.

'But the effects on the adult man remain largely unknown.

Now, before you panic, there's no suggestion yet that occasionally relying on an ibuprofen will make your balls shrivel up and die. Long term, it can lead to a more serious condition called overt primary hypogonadism, which is characterized by low testosterone and libido, depressed mood and reduced muscle mass and strength.

When struggling to get pregnant, couples will immediately try to find the source of the issue, but a small new study has revealed that ibuprofen could be a potential sperm killer, and it's something all trying couples should read. So not only is the shrinking of your balls concerning on a personal level, it could also suggest you're going to die earlier. "Taken together, these in vivo data suggest that ibuprofen induced a state of compensated hypogonadism during the trial..." the study states. But researchers are concerned about long-term use among athletes.

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